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Sexual risk taking behaviour: prevalence and associated factors. A...

AbstractBackgroundSexual habits and risky sexual behaviour strongly affect public health. Available data indicate that sexually transmitted infections are increasing in many EU countries. Changes in...

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Increased incidence of penile cancer and high-grade penile intraepithelial...

AbstractObjectiveTo assess the trends in incidence of penile cancer during 1978–2008 and high-grade penile intraepithelial neoplasia (PIN2/3) during 1998–2008 in Denmark.MethodsUsing two nationwide...

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Questionable evidence of increasing incidence of invasive penile cancer in...

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Carcinogenic HPV prevalence and age-specific type distribution in 40,382...

AbstractBackgroundAssessment of the prevaccination type-specific prevalence of human papillomavirus (HPV) in the general population is important for the prediction of the impact of HPV...

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Incidence of cervical lesions in Danish women before and after implementation...

AbstractPurposeApproximately 70 % of cervical cancers and about 50 % of high-grade cervical precursor lesions are caused by human papillomavirus (HPV) types 16 and 18. Denmark introduced the...

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Trends in the incidence of cervical cancer and severe precancerous lesions in...

AbstractPurposeThe incidence of cervical cancer, including squamous cell carcinoma (SCC), has been decreasing in several developed countries since the onset of organized screening programs; in some...

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Risk of breast cancer among women with benign ovarian tumors: a Danish...

AbstractPurposeTo assess the association between benign ovarian tumors and subsequent risk of breast cancer, and to examine this association according to type of benign ovarian tumors.MethodsThis...

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Ovarian removal at or after benign hysterectomy and breast cancer: a...

AbstractPurposeLarge-scale population-based registry studies investigating the risk of breast cancer after removal of both ovaries at hysterectomy for benign conditions in women with no known genetic...

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Incidence of penile intraepithelial neoplasia and incidence and survival of...

AbstractPurposeSquamous cell carcinoma (SCC) of the penis is rare. Some studies have suggested that the incidence is increasing but the available literature is equivocal. We examined the incidence of...

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Ovarian removal and subsequent breast cancer prognosis: a nationwide cohort...

AbstractPurposeTo evaluate whether previous ovarian removal concomitant with benign hysterectomy improves prognosis in a cohort of women with breast cancer.MethodsIn this nationwide register-based...

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An online resource for GPCR structure determination and analysis

AbstractG-protein-coupled receptors (GPCRs) transduce physiological and sensory stimuli into appropriate cellular responses and mediate the actions of one-third of drugs. GPCR structural studies have...

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Combinatorial expression of GPCR isoforms affects signalling and drug responses

AbstractG-protein-coupled receptors (GPCRs) are membrane proteins that modulate physiology across human tissues in response to extracellular signals. GPCR-mediated signalling can differ because of...

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Author Correction: Combinatorial expression of GPCR isoforms affects...

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

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GPCR activation mechanisms across classes and macro/microscales

AbstractTwo-thirds of human hormones and one-third of clinical drugs activate ~350 G-protein-coupled receptors (GPCR) belonging to four classes: A, B1, C and F. Whereas a model of activation has been...

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An online GPCR structure analysis platform

AbstractWe present an online, interactive platform for comparative analysis of all available G-protein coupled receptor (GPCR) structures while correlating to functional data. The comprehensive...

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